Do Patients with Chronic Liver Disease Face Higher Drug-induced Liver Injury Risk?

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Do Patients with Chronic Liver Disease Face Higher Drug-induced Liver Injury Risk?

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Do Patients with Chronic Liver Disease Face Higher DILI Risk? 
by Molly Walker, Staff Writer, MedPage Today
November 12, 2018
Research suggests a link of which drug developers should be aware, expert says

SAN FRANCISCO -- Individuals with certain types of chronic liver disease may be particularly susceptible to drug-induced liver injury (DILI), and the pharmaceutical industry should take this population into account during drug development, an expert said here.

Indeed, some research suggested that drug-induced liver injury is linked with a higher risk of poor outcomes in patients with pre-existing liver disease, said Naga Chalasani, MD, of Indiana University School of Medicine in Indianapolis.
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